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I am not allergic, I have never had allergies or reactions to any skincare products, but after using this serum - it happened for the first time! I applied it in the morning after cleansing and toning, deliberately using only a few drops from the dropper. Within minutes, red spots appeared on my skin, which disappeared after 3-4 hours. The grand finale was waking up the next day with small red painful pimples all over my face... Of course, everyone is different, but ladies, it's better to test it on your arm first.